中文名称: RASA1抗原(重组蛋白)
英文名称:RASA1 Antigen (Recombinant Protein)
别 名:RAS p21 protein activator (GTPase activating protein) 1; GAP; PKWS; RASA; CMAVM; CM-AVM; RASGAP; p120GAP; p120RASGAP
储 存:冷冻(-20℃)
相关类别:抗原
概 述:Fusion protein corresponding to a region derived from 748-1047 amino acids of human RASA1技术规格:RASA1抗原(重组蛋白)
Full name:
RAS p21 protein activator (GTPase activating protein) 1
Synonyms:
GAP; PKWS; RASA; CMAVM; CM-AVM; RASGAP; p120GAP; p120RASGAP
Swissprot:
P20936
Gene Accession:
BC033015
Purity:
>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:
Escherichia coli
Tags:
His tag C-Terminus, GST tag N-Terminus
Background:
The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.
产品标签
用户评论(共6条评论)
- AKR1B1抗原(重组蛋白)
- ANKRD1抗原(重组蛋白)
- ASB9抗原(重组蛋白)
- AIF1抗原(重组蛋白)
- ATP6V0D1抗原(重组蛋白)
- ADAP1抗原(重组蛋白)
- APOC1抗原(重组蛋白)
- ARHGDIA抗原(重组蛋白)
- AKR1B10抗原(重组蛋白)
- ANGPTL4抗原(重组蛋白)
- ABCC6抗原(重组蛋白)
- ADAM7抗原(重组蛋白)
- BOLL抗原(重组蛋白)
- ADD1抗原(重组蛋白)
- ARF6抗原(重组蛋白)
- BIRC7抗原(重组蛋白)
- AKR1D1抗原(重组蛋白)
- ATP6V1E2抗原(重组蛋白)
- ATOX1抗原(重组蛋白)
- AURKAIP1抗原(重组蛋白)
- ANXA1抗原(重组蛋白)
- ARL11抗原(重组蛋白)
- B2M抗原(重组蛋白)
- AASDHPPT抗原(重组蛋白)
- ARMC10抗原(重组蛋白)
- ALKBH8抗原(重组蛋白)
- ANXA2抗原(重组蛋白)
- A4GALT 抗原(重组蛋白)
- ANAPC10抗原(重组蛋白)
- APIP抗原(重组蛋白)
- AKAP9抗原(重组蛋白)
- ANAPC13抗原(重组蛋白)
- ANGPT1抗原(重组蛋白)
- ARL2抗原(重组蛋白)
- ACSBG2抗原(重组蛋白)
- ARF4抗原(重组蛋白)
- BID抗原(重组蛋白)
- BCAS2抗原(重组蛋白)
- ACTG1抗原(重组蛋白)
- BCL10抗原(重组蛋白)
- ACY3抗原(重组蛋白)
- ADAM17抗原(重组蛋白)
- ACP3抗原(重组蛋白)
- ACOT8抗原(重组蛋白)
- ASPA抗原(重组蛋白)
- AP2S1抗原(重组蛋白)
- ANXA10抗原(重组蛋白)
- ACMSD抗原(重组蛋白)
- ASF1A抗原(重组蛋白)
- ARL8A抗原(重组蛋白)
- ARL6抗原(重组蛋白)
- ATG5抗原(重组蛋白)
- AGER抗原(重组蛋白)
- ATG12抗原(重组蛋白)
- ANP32A抗原(重组蛋白)
- ACVR1B抗原(重组蛋白)
- ACBD4抗原(重组蛋白)
- ACOT2抗原(重组蛋白)
- ALKBH2抗原(重组蛋白)
- ACAD10抗原(重组蛋白)
上海酶联生物科技有限公司
Shanghai Enzyme-linked Biotechnology Co., Ltd.
订购热线:4008-898-798 / 021-54720761
传 真:021-54222852
地址:上海市松江区云凯路66号T2楼1603室
酶联官方手机二维码
微信扫描二维码,参与酶联活动,
劲爆优惠触手可得!
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。